Rosana Souza Rodrigues

Rosana Souza Rodrigues

Research

Our studies focus mainly on morphological and functional evaluation of pulmonary inflammation in clinical and experimental models using chest computed tomography (CT) and positron emission tomography with CT (PET-CT) as imaging tools. We use PET-CT to characterize biological processes at the cellular and molecular levels to investigate pulmonary inflammation’s physiopathological mechanisms. These studies are based on the assumption that the development of inflammation in the lung is prior to the development of tomographic changes, and it may be identified non-invasively. Our group also develops computer-aided diagnosis (CAD) systems for automated semantic segmentation, classification, and quantification of pulmonary involvement using deep learning algorithms.

Keywords: pulmonary inflammation, computed tomography, PET-CT, molecular imaging, artificial intelligence

EDUCATION

MD, Medicine, Federal University of Rio de Janeiro, Brazil

PhD, Department of Radiology, Federal University of Rio de Janeiro, Brazil

Postdoctoral fellow, University of Pittsburgh, USA

INVESTIGATION AREAS

Internal Medicine

ADITIONAL INFORMATION

Selected Publications

Carvalho, ARS ; Guimarães, A; Garcia, TSO; Madeira, GW; Ceotto, VF; Bozza, FA; Rodrigues, RS; Pinto, JSF; Schmitt, WR ; Zin, WA; França, M. Estimating COVID-19 Pneumonia Extent and Severity from Chest Computed Tomography. Frontiers in Physiology, v. 12, p. 1, 2021.

Carvalho, ARS; Guimarães, A; Werberich, GM, F, SJ; Schmitt, WR ; França, M; Bozza, FA; Guimarães, BLS; Zin, WA; Rodrigues, RS. COVID-19 Chest Computed Tomography to Stratify Severity and Disease Extension by Artificial Neural Network Computer-Aided Diagnosis. Frontiers in Medicine, v. 7, p. 1, 2020.

Carvalho, ARS; Guimarães, A; Sztajnbok, FR; Rodrigues, RS, Silva, BRA; Lopes, AJ; Zin, WA; Almeida, I; França, MM . Automatic uantification of Interstitial Lung Disease from Chest Computed Tomography in Systemic Sclerosis. Frontiers in Medicine, v. 7, p. 1, 2020.

Wang, L; Wu, Q; Kirk, RA; Horn, KP; Hoffman, JM; Towner, RA; Bozza, FA, Rodrigues, RS; Morton, KA. Lipopolysaccharide endotoxemia induces amyloid-β and p-tau formation in the rat brain. Am J Nucl Med Mol Imaging, v. 8, p. 86-99, 2018.

Silva, BRA; Rodrigues, RS; Rufino, R; Costa, CH ; Vilela, VS; Levy, RA; Guimarães, ARM; Carvalho, ARS; Lopes, AJ . Computed tomography trachea volumetry in patients with scleroderma: Association with clinical and functional findings. PLoS One, v. 13, p. e0200754, 2018.

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