Stevens Rehen

Stevens Rehen

Stevens Rehen is a neuroscientist at the D’Or Institute for Research and Education (IDOR) in Brazil, and serves as a Research Fellow at both Promega Corporation and the Usona Institute. He is an Affiliated Member of the Latin American Academy of Sciences and the Academy of Sciences for the Developing World (TWAS). Among his honors are the National Order of Scientific Merit (Commander, Brazil) and the PEW Latin American Program Fellowship in Biomedical Sciences. He holds an unpaid professorship at the Federal University of Rio de Janeiro and has been recognized with the International Fiocruz Servier Award for Neurosciences and a Fulbright Visiting Professor Award. Stevens Rehen is Member of the Committee of the Museum of Tomorrow. He also served as President of the Brazilian Society for Neuroscience and Behavior. His current research focus is on the effects of psychedelics on human cerebral organoids and Caenorhabditis elegans.

Keywords: human induced pluripotent stem cells; brain organoids; neurospheres; neuroscience; Zika virus

EDUCATION

Federal University of Rio de Janeiro, Ph.D., Biological Sciences

University of California in San Diego, Postdoctoral Training, Neuroscience

The Scripps Research Institute, Postdoctoral Training, Neuroscience

INVESTIGATION AREAS

Neurosciences

ADITIONAL INFORMATION

AWARDS AND HONORS

Medalha Nacional do Mérito Científico - Classe Comendador, Ordem Nacional do Mérito Científico. 2023.

Prêmio Jovem Pesquisador Promega Brasil. 2021.

Fulbright Visiting Professor Award. 2021.

International Fiocruz Servier Award for the Neurosciences. 2018.

Affiliated Member of Latin American Academy of Sciences. 2017.

Selected Publications

Karmirian K, Holubiec M, Goto-Silva L, Fernandez Bessone I, Vitória G, Mello B, Alloatti M, Vanderborght B, Falzone TL, Rehen S. Modeling Alzheimer’s Disease Using Human Brain Organoids. Methods Mol Biol. 2023;2561:135-158. PMID: 36399268.
doi: 10.1007/978-1-0716-2655-9_7

Ornelas IM, Cini FA, Wießner I, Marcos E, Araújo DB, Goto-Silva L, Nascimento J, Silva SRB, Costa MN, Falchi M, Olivieri R, Palhano-Fontes F, Sequerra E, Martins-de-Souza D, Feilding A, Rennó-Costa C, Tófoli LF, Rehen SK, Ribeiro S. Nootropic effects of LSD: Behavioral, molecular and computational evidence. Exp Neurol. 2022 Oct;356:114148. Epub 2022 Jun 19. PMID: 35732217.
doi: 10.1016/j.expneurol.2022.114148

Ornelas IM, Carrilho BS, Ventura MAVC, Domith I, de V Silveira CM, Dos Santos VF, Delou JM, Moll F, Pereira HMG, Junqueira M, Aguilaniu H, Rehen S. Lysergic acid diethylamide induces behavioral changes in Caenorhabditis elegans. Neurosci Lett. 2024 Aug 10;837:137903. Epub 2024 Jul 20. PMID: 39025433.
doi: 10.1016/j.neulet.2024.137903.

N. Costa M, Goto-Silva L, M. Nascimento J, Domith I, Karmirian K, Feilding A, Trindade P, Martins-de-Souza D, K. Rehen S. LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Cerebral Organoids. ACS Omega. (2024).
doi: 10.1021/acsomega.4c04712

Salerno JA, Rehen S. Human pluripotent stem cells as a translational toolkit in psychedelic research in vitroiScience. 2024 Mar 28;27(5):109631. PMID: 38628967; PMCID: PMC11019282.
doi: 10.1016/j.isci.2024.109631

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