Roberto Lent

Roberto Lent


Roberto Lent studies mechanisms of neuroplasticity in animals and humans, along development and aging.

Keywords: Corpus callosum, neuroplasticity, cerebral cortex, development


MD, MSc, PhD, all at Federal University of Rio de Janeiro.





Emeritus Professor, Federal University of Rio de Janeiro (2019)

Persons of the Year 2014 (Faz a Diferença), O Globo newspaper (2014)

José Reis National Prize of Science Popularization (2010)

TWAS Prize for Public Understanding and Science Popularization , Third World Academy of Sciences(2007)

National Medal of National Scientific Merit, Brazilian President of the Republic (2000)

Selected Publications

Azevedo FA, Carvalho LR, Grinberg LT, Farfel JM, Ferretti RE, Leite RE, Jacob Filho W, Lent R, Herculano-Houzel S. Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain. J Comp Neurol. 2009 Apr 10;513(5):532-41. PMID: 19226510.
doi: 10.1002/cne.21974

Lent R, Azevedo FA, Andrade-Moraes CH, Pinto AV. How many neurons do you have? Some dogmas of quantitative neuroscience under revision. Eur J Neurosci. 2012 Jan;35(1):1-9. Epub 2011 Dec 13. PMID: 22151227.
doi: 10.1111/j.1460-9568.2011.07923.x

Andrade-Moraes CH, Oliveira-Pinto AV, Castro-Fonseca E, da Silva CG, Guimarães DM, Szczupak D, Parente-Bruno DR, Carvalho LR, Polichiso L, Gomes BV, Oliveira LM, Rodriguez RD, Leite RE, Ferretti-Rebustini RE, Jacob-Filho W, Pasqualucci CA, Grinberg LT, Lent R. Cell number changes in Alzheimer’s disease relate to dementia, not to plaques and tangles. Brain. 2013 Dec;136(Pt 12):3738-52. Epub 2013 Oct 17. PMID: 24136825; PMCID: PMC3859218.
doi: 10.1093/brain/awt273

Tovar-Moll F, Monteiro M, Andrade J, Bramati IE, Vianna-Barbosa R, Marins T, Rodrigues E, Dantas N, Behrens TE, de Oliveira-Souza R, Moll J, Lent R. Structural and functional brain rewiring clarifies preserved interhemispheric transfer in humans born without the corpus callosum. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7843-8. Epub 2014 May 12. PMID: 24821757; PMCID: PMC4040546.
doi: 10.1073/pnas.1400806111

Szczupak D, Liu C, Yen CCC, Choi SH, Meireles F, Victorino C; IRC5 Consortium; Richards L, Lent R, Silva AC, Tovar-Moll F. Long-distance aberrant heterotopic connectivity in a mouse strain with a high incidence of callosal anomalies. Neuroimage. 2020 Aug 15;217:116875. Epub 2020 Apr 23. PMID: 32335262; PMCID: PMC7590260.
doi: 10.1016/j.neuroimage.2020.116875

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